| Incidence and characteristics of appropriate and inappropriate therapies in recipients of ICD implanted for primary prevention of sudden cardiac death. | |
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MedLine Citation:
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PMID: 17302687 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: We evaluated the number of appropriate and inappropriate therapies for ventricular tachyarrhythmias and trigger mechanisms in 55 MADIT II (MII)-like (group 1) and 86 SCD-HeFT-like (group 2) patients. METHODS AND RESULTS: We analyzed 399 appropriate episodes in 31 patients with implantable cardioverter defibrillators (ICD) implanted according to the MII trial indications, and 502 appropriate episodes in 47 patients matching the SCD-HeFT trial criteria (mean follow-up in both groups = 33 +/- 19 months). In group 1, 39 treated episodes were inappropriate (9% of all episodes), while in group 2, 76 episodes were treated inappropriately (15% of all episodes). At least one episode of inappropriate ICD therapy was recorded in 18% of patients in group 1 (n = 10) and in 22% of patients in group 2 (n = 19). CONCLUSIONS: Our study supports the implantation of ICD as primary prevention in patients who are at risk of sudden cardiac death, although the proportion of inappropriate ICD interventions remains high. |
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Authors:
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Jens Kreuz; Osman Balta; Nora Liliegren; Fritz Mellert; Bahman Esmailzadeh; Georg Nickenig; Jörg Otto Schwab |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 30 Suppl 1 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-02-16 Completed Date: 2007-06-12 Revised Date: 2008-01-18 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: S125-7 Citation Subset: IM |
Affiliation:
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Department of Medicine-Cardiology, University of Bonn, Bonn, Germany. jekreuz@yahoo.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Death, Sudden, Cardiac / prevention & control* Defibrillators, Implantable / utilization* Female Humans Male Middle Aged Patient Selection Retrospective Studies Tachycardia, Ventricular / therapy* |
| Comments/Corrections | |
Erratum In:
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Pacing Clin Electrophysiol. 2007 Nov;30(11):1427 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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