Document Detail


Incidence and characteristics of appropriate and inappropriate therapies in recipients of ICD implanted for primary prevention of sudden cardiac death.
MedLine Citation:
PMID:  17302687     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: We evaluated the number of appropriate and inappropriate therapies for ventricular tachyarrhythmias and trigger mechanisms in 55 MADIT II (MII)-like (group 1) and 86 SCD-HeFT-like (group 2) patients. METHODS AND RESULTS: We analyzed 399 appropriate episodes in 31 patients with implantable cardioverter defibrillators (ICD) implanted according to the MII trial indications, and 502 appropriate episodes in 47 patients matching the SCD-HeFT trial criteria (mean follow-up in both groups = 33 +/- 19 months). In group 1, 39 treated episodes were inappropriate (9% of all episodes), while in group 2, 76 episodes were treated inappropriately (15% of all episodes). At least one episode of inappropriate ICD therapy was recorded in 18% of patients in group 1 (n = 10) and in 22% of patients in group 2 (n = 19). CONCLUSIONS: Our study supports the implantation of ICD as primary prevention in patients who are at risk of sudden cardiac death, although the proportion of inappropriate ICD interventions remains high.
Authors:
Jens Kreuz; Osman Balta; Nora Liliegren; Fritz Mellert; Bahman Esmailzadeh; Georg Nickenig; Jörg Otto Schwab
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  30 Suppl 1     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-02-16     Completed Date:  2007-06-12     Revised Date:  2008-01-18    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S125-7     Citation Subset:  IM    
Affiliation:
Department of Medicine-Cardiology, University of Bonn, Bonn, Germany. jekreuz@yahoo.de
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MeSH Terms
Descriptor/Qualifier:
Aged
Death, Sudden, Cardiac / prevention & control*
Defibrillators, Implantable / utilization*
Female
Humans
Male
Middle Aged
Patient Selection
Retrospective Studies
Tachycardia, Ventricular / therapy*
Comments/Corrections
Erratum In:
Pacing Clin Electrophysiol. 2007 Nov;30(11):1427

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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