Document Detail

Incidence and characteristics of appropriate and inappropriate therapies in recipients of ICD implanted for primary prevention of sudden cardiac death.
MedLine Citation:
PMID:  17302687     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We evaluated the number of appropriate and inappropriate therapies for ventricular tachyarrhythmias and trigger mechanisms in 55 MADIT II (MII)-like (group 1) and 86 SCD-HeFT-like (group 2) patients. METHODS AND RESULTS: We analyzed 399 appropriate episodes in 31 patients with implantable cardioverter defibrillators (ICD) implanted according to the MII trial indications, and 502 appropriate episodes in 47 patients matching the SCD-HeFT trial criteria (mean follow-up in both groups = 33 +/- 19 months). In group 1, 39 treated episodes were inappropriate (9% of all episodes), while in group 2, 76 episodes were treated inappropriately (15% of all episodes). At least one episode of inappropriate ICD therapy was recorded in 18% of patients in group 1 (n = 10) and in 22% of patients in group 2 (n = 19). CONCLUSIONS: Our study supports the implantation of ICD as primary prevention in patients who are at risk of sudden cardiac death, although the proportion of inappropriate ICD interventions remains high.
Jens Kreuz; Osman Balta; Nora Liliegren; Fritz Mellert; Bahman Esmailzadeh; Georg Nickenig; Jörg Otto Schwab
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  30 Suppl 1     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-02-16     Completed Date:  2007-06-12     Revised Date:  2008-01-18    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S125-7     Citation Subset:  IM    
Department of Medicine-Cardiology, University of Bonn, Bonn, Germany.
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MeSH Terms
Death, Sudden, Cardiac / prevention & control*
Defibrillators, Implantable / utilization*
Middle Aged
Patient Selection
Retrospective Studies
Tachycardia, Ventricular / therapy*
Erratum In:
Pacing Clin Electrophysiol. 2007 Nov;30(11):1427

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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