Document Detail


Incidence of cerebral embolism after cardioversion of atrial fibrillation: a prospective study with transesophageal echocardiography and cerebral magnetic resonance imaging.
MedLine Citation:
PMID:  15947768     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: After cardioversion of atrial fibrillation the risk for cerebral embolism is increased. There is little knowledge about the incidence of cerebral embolism for patients with transesophageal echocardiography (TEE)-guided cardioversion under oral anticoagulation. METHODS: Consecutive patients with atrial fibrillation and TEE-guided cardioversion were included in the study. We performed serial TEE studies, Holter electrocardiography, cranial magnetic resonance imaging, and clinical examinations during a period of 4 weeks before and after cardioversion. Oral anticoagulation was continued or initiated in all patients. RESULTS: During the observation period 6 of 127 (4.7%) patients had new embolic lesions after cardioversion documented on cerebral magnetic resonance imaging. Patients with an event were significantly older (P = .04) and had a larger left atrium (P = .04) than patients without event. CONCLUSION: Patients with atrial fibrillation and oral anticoagulation have a low rate of clinical apparent cerebral embolism after TEE and anticoagulation-guided cardioversion. The rate of silent cerebral embolism is almost 5%. Age and left atrial size are predictors for an event.
Authors:
Peter Bernhardt; Harald Schmidt; Christoph Hammerstingl; Berndt Lüderitz; Heyder Omran
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  18     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-10     Completed Date:  2006-04-11     Revised Date:  2007-11-02    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  649-53     Citation Subset:  IM    
Affiliation:
Department of Medicine-Cardiology, University of Bonn, Bonn, Germany. bernhardt@cardiomrt.de
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MeSH Terms
Descriptor/Qualifier:
Administration, Oral
Anticoagulants / administration & dosage
Atrial Fibrillation / diagnosis*,  epidemiology,  therapy*
Comorbidity
Echocardiography, Transesophageal / statistics & numerical data*
Electric Countershock / statistics & numerical data*
Female
Germany / epidemiology
Humans
Incidence
Intracranial Embolism / diagnosis*,  epidemiology*,  prevention & control
Magnetic Resonance Imaging / statistics & numerical data*
Male
Middle Aged
Prospective Studies
Risk Assessment / methods
Risk Factors
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anticoagulants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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