Document Detail


Incidence of bleeding lesions within reach of conventional upper and lower endoscopes in patients undergoing double-balloon enteroscopy for obscure gastrointestinal bleeding.
MedLine Citation:
PMID:  19035975     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Double-balloon enteroscopy (DBE) is a useful method for evaluation of obscure gastrointestinal bleeding (OGIB). AIM: To determine the incidence of lesions within reach of conventional upper and lower endoscopes as the cause of OGIB in patients referred for DBE. METHODS: All patients undergoing DBE for OGIB during a 3.5-year period at a university hospital were studied. OGIB was defined according to American Gastroenterological Association (AGA) guidelines. RESULTS: One hundred and forty-three DBEs were performed in 107 patients for obscure overt (n=85) and obscure occult (n=22) GIB. Lesions outside the SB as possible sources of GIB were found in 51 patients (47.6%) and a definite source of bleeding outside the small bowel (SB) was detected in 26 patients (24.3%). Lesions considered to explain a definite source of GIB were: gastric ulcer (n=3), duodenal ulcer (n=3), Cameron's lesions (n=2), gastric antral vascular ectasias (n=4), radiation proctitis (n=1), radiation ileitis (n=2), duodenal angiodysplasias (n=1), haemorrhoids with stigmata of recent bleed (n=1), colon angiodysplasias (n=3), colon diverticulosis (n=3), colonic Crohn's disease (n=1), anastomotic ulcers (n=1). CONCLUSIONS: The frequency of non-SB lesions definitely explaining the source of GIB in patients referred for DBE was 24.3%. Therefore, repeat esophago-gastroduodenoscopy (EGD) and ileocolonoscopy should be taken into consideration before DBE.
Authors:
L C Fry; M Bellutti; H Neumann; P Malfertheiner; K Mönkemüller
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Publication Detail:
Type:  Journal Article     Date:  2008-11-13
Journal Detail:
Title:  Alimentary pharmacology & therapeutics     Volume:  29     ISSN:  1365-2036     ISO Abbreviation:  Aliment. Pharmacol. Ther.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-01-09     Completed Date:  2009-04-02     Revised Date:  2009-04-16    
Medline Journal Info:
Nlm Unique ID:  8707234     Medline TA:  Aliment Pharmacol Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  342-9     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University, Magdeburg, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Balloon Dilatation / adverse effects*,  methods
Diagnosis, Differential
Endoscopy, Gastrointestinal / adverse effects*,  methods
Female
Gastrointestinal Hemorrhage / etiology*
Humans
Male
Middle Aged
Prospective Studies
Treatment Outcome
Young Adult
Comments/Corrections
Comment In:
Aliment Pharmacol Ther. 2009 Apr 15;29(8):918-9; author reply 919-20   [PMID:  19338648 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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