Document Detail

Incidence of bacteraemia following endobronchial ultrasound-guided transbronchial needle aspiration.
MedLine Citation:
PMID:  19926733     Owner:  NLM     Status:  MEDLINE    
Few data exist concerning possible infectious complications associated with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). The present prospective evaluation was undertaken in order to determine the incidence of bacteraemia and infectious complications associated with EBUS-TBNA. Consecutive patients undergoing EBUS-TBNA for evaluation of mediastinal or hilar lymph node lesions were studied. Venesection was performed within 60 s of TBNA for aerobic and anaerobic blood culture. Sterile saline washing of TBNA needles was also performed. Patients with positive blood cultures were reviewed immediately, and all patients underwent clinical review within 1 week of EBUS-TBNA. A total of 43 patients underwent EBUS-TBNA, with bacteraemia demonstrated in three (7%). All bacterial isolates were typical oropharyngeal commensal organisms. The TBNA needle washing culture was positive in 15 (35%) patients. None of the three bacteraemic patients had clinical features suggestive of infection, and no complications were seen among the cohort. The incidence of bacteraemia following EBUS-TBNA is comparable to that following routine flexible bronchoscopy. Performance of TBNA does not appear to measurably increase the risk of bacteraemia over that associated with insertion of the bronchoscope into the airway. Contamination of the TBNA needle with oropharyngeal commensal bacteria is common; however, clinically significant infection following EBUS-TBNA appears rare.
D P Steinfort; D F Johnson; L B Irving
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Publication Detail:
Type:  Journal Article     Date:  2009-11-19
Journal Detail:
Title:  The European respiratory journal     Volume:  36     ISSN:  1399-3003     ISO Abbreviation:  Eur. Respir. J.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-02     Completed Date:  2010-10-21     Revised Date:  2013-05-23    
Medline Journal Info:
Nlm Unique ID:  8803460     Medline TA:  Eur Respir J     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  28-32     Citation Subset:  IM    
Dept of Respiratory Medicine, Level 1, Centre for Medical Research Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.
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MeSH Terms
Bacteremia / epidemiology*,  etiology
Biopsy, Needle / adverse effects*
Bronchoscopy / adverse effects*,  methods
Lymph Nodes / pathology
Mediastinum / pathology
Middle Aged
Oropharynx / microbiology*

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