| Incidence of arterial cardiovascular events after venous thromboembolism: a systematic review and a meta-analysis. | |
| | |
MedLine Citation:
|
PMID: 20095999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
SUMMARY BACKGROUND: Whether patients with unprovoked venous thromboembolism (VTE) have a higher risk of arterial cardiovascular events than the general population and patients with provoked VTE is a matter of debate. OBJECTIVE: To perform a systematic review and a meta-analysis aimed at assessing the risk of arterial cardiovascular events in patients with unprovoked VTE as compared with both patients with provoked VTE and controls. METHODS: A systematic search was performed. Studies reporting on (i) patients with confirmed VTE, (ii) a follow-up of at least 6 months and (iii) the incidence of arterial cardiovascular events (acute myocardial infarction and ischemic stroke) were included in the systematic review. Those studies reporting separate incidences of cardiovascular events in patients with unprovoked and provoked VTE or patients with unprovoked VTE and controls were included in the incidence rate meta-analysis. RESULTS: Overall, 17 studies were included in the systematic review. The weighted mean incidence of arterial cardiovascular events was 0.46% [95% confidence interval (CI) 0.34-0.59] and 0.35% (95% CI 0.24-0.49) per patient-year in patients with unprovoked and provoked VTE, respectively. Six studies were included in the meta-analysis. The risk of arterial cardiovascular events appeared to be higher in patients with unprovoked VTE than in controls [incidence rate ratio (IRR) 1.87, 95% CI 1.32-2.65] and than in patients with provoked VTE (IRR 1.86, 95% CI 1.19-2.89). CONCLUSIONS: Patients with unprovoked VTE have a higher risk of arterial cardiovascular events than patients with provoked VTE over long-term follow-up. |
| | |
Authors:
|
C Becattini; M C Vedovati; W Ageno; F Dentali; G Agnelli |
Related Documents
:
|
18383049 - Prognostic value of troponins in patients with non-st-segment elevation acute coronary ... 12551859 - Should volume standards for cardiovascular surgery focus only on high-risk patients? 15911729 - Bezafibrate for the secondary prevention of myocardial infarction in patients with meta... 16489569 - Outcomes of contrast-induced nephropathy: experience in patients undergoing cardiovascu... 18362419 - Impact of body mass index on in-hospital outcomes after percutaneous coronary intervent... 19327309 - Comparative evaluation of glasgow coma score and gag reflex in predicting aspiration pn... 831239 - Lower blepharoplasty--a clinical study. 11761019 - Reduced plasma antioxidant concentrations and increased oxidative dna damage in inflamm... 11683689 - Involvement of the corporal mucosa and related changes in gastric acid secretion charac... |
Publication Detail:
|
Type: Journal Article; Meta-Analysis; Review Date: 2010-01-22 |
Journal Detail:
|
Title: Journal of thrombosis and haemostasis : JTH Volume: 8 ISSN: 1538-7836 ISO Abbreviation: J. Thromb. Haemost. Publication Date: 2010 May |
Date Detail:
|
Created Date: 2010-06-22 Completed Date: 2010-10-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101170508 Medline TA: J Thromb Haemost Country: England |
Other Details:
|
Languages: eng Pagination: 891-7 Citation Subset: IM |
Affiliation:
|
Division of Internal and Cardiovascular Medicine & Stroke Unit, University of Perugia, Varese, Italy. cecilia.becattini@unipg.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Arteries
/
pathology* Cohort Studies Humans Incidence Vascular Diseases / etiology* Venous Thromboembolism / complications* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Plasminogen on the surface of fibrin clot prevents adhesion of leukocytes and platelets.
Next Document: Risk of stroke after surgery in patients with and without chronic atrial fibrillation.