Document Detail


Incidence of arm lymphoedema following sentinel node biopsy, axillary sampling and axillary dissection in patients with breast cancer.
MedLine Citation:
PMID:  20023249     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to compare the incidence of lymphoedema after different treatments of the axilla in patients with breast cancer (BC). Medical records of 205 women (median age 61 years, range 26-72 years) who underwent curative surgery for primary BC were reviewed. According to the treatment of the axilla, the study population was divided into four age- and stage-matched groups of patients: Group A (N=54 patients), sentinel node biopsy (SLNB) alone; Group B (N=48 patients), SLNB followed by axillary node (AN) sampling using ultrasound scissors (harmonic scalpel); Group C (N=53 patients), AN dissection using ultrasound scissors; Group D (N=50 patients), traditional AN dissection. The median follow-up was 22 months (range 18-28 months). The intraoperative frozen section of SLNB (Groups A and B) showed 32 out of 102 (31.4%) patients with metastasis to AN, while final pathology showed AN metastases in 20, 17, 16 and 17 patients of groups A, B, C and D, respectively (p=NS). The sensitivity of SLNB alone was 80% and that of SLNB followed by AN sampling was 95% (p=NS). At follow-up patients with lymphoedema were 2 (3.7%), 2 (4.2%), 3 (5.6%) and 8 (16%) in groups A, B, C and D, respectively (p=NS). In conclusion, AN sampling is a sensitive and low-morbidity procedure which, in conjunction with the use of harmonic scalpel, may reduce the onset of arm lymphoedema.
Authors:
Franco Lumachi; Stefano M M Basso; Manuela Bonamini; Filippo Marino; Bernardo Marzano; Elisa Milan; Beata U Waclaw; Giordano B Chiara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  In vivo (Athens, Greece)     Volume:  23     ISSN:  0258-851X     ISO Abbreviation:  In Vivo     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-12-21     Completed Date:  2010-03-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806809     Medline TA:  In Vivo     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  1017-20     Citation Subset:  IM    
Affiliation:
Department of Surgical and Gastroenterological Sciences, University of Padua, School of Medicine, 35128 Padova, Italy. flumachi@unipd.it
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / diagnosis*,  secondary,  surgery
Adult
Aged
Axilla / surgery
Breast Neoplasms / diagnosis*,  surgery
Female
Humans
Italy / epidemiology
Lymph Node Excision / adverse effects
Lymphatic Metastasis / diagnosis
Lymphedema / epidemiology,  etiology*,  pathology
Middle Aged
Postoperative Complications / epidemiology,  etiology*,  pathology
Sentinel Lymph Node Biopsy / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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