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Incidence of Pulmonary Embolism in an Emergency Department Cohort Evaluated with a Simple Symptom-based Diagnostic Algorithm.
MedLine Citation:
PMID:  23422481     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
BACKGROUND: Although complex scores were recommended for diagnosis of pulmonary embolism (PE), acceptance in clinical practice is limited. In our Emergency Department a symptom-based algorithm for patients with suspected PE including computed tomographic pulmonary angiography (CTPA) and D-dimer testing was implemented.
PATIENTS AND METHODS: The cases of 492 patients presenting with either chest pain, dyspnea or syncope for whom this algorithm was applied, were retrospectively analyzed with respect to the incidence of PE, D-dimer and high-sensitive troponin levels.
RESULTS: Our algorithm detected PE in 59 out of 492 patients. D-Dimer levels were significantly higher in the PE group than in the patients without PE (p<0.0001). High-sensitive troponin was significantly increased in patients with central PE compared to other patients (p<0.01).
CONCLUSION: Our data demonstrate the utility and practicability of our symptom-based algorithm in combination with D-dimer testing and the use of CTPA in patients with suspected PE.
Authors:
Joachim Gruettner; Thomas Walter; Merle Bolte; Dariush Haghi; Sonja Sudarski; Thomas Henzler
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  In vivo (Athens, Greece)     Volume:  27     ISSN:  1791-7549     ISO Abbreviation:  In Vivo     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806809     Medline TA:  In Vivo     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  215-20     Citation Subset:  IM    
Affiliation:
University Medical Centre Mannheim, Emergency Department, Medical Faculty Mannheim, Heidelberg University, Theodor Kutzer Ufer 1 3, D 68167 Mannheim, Germany. joachim.gruettner@umm.de.
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