| Incidence of late thromboembolic events after catheter ablation of atrial fibrillation. | |
| | |
MedLine Citation:
|
PMID: 21778595 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: A low incidence of thromboembolic events after successful catheter ablation of atrial fibrillation (AF) during a mid-term follow-up period was recently reported. However, because the incidence of such events over the long term is unknown, we investigated the late incidence of thromboembolic events after catheter ablation. METHODS AND RESULTS: Patients with paroxysmal and persistent AF undergoing catheter ablation and being followed up for at least 24 months formed the study group (n = 524); 82 patients (16%) had CHADS₂ scores of at least 2. Mean follow-up was 44 ± 13 months. Warfarin was discontinued in 400 (93%) of 429 patients (82% of 524 patients) without AF recurrence. None of the patients without AF recurrence suffered thromboembolic events, whereas 3 of 95 patients (3%) with AF recurrence did (P < 0.001). One of the 3 was a late AF recurrence occurring > 12 months after catheter ablation. There were 2 nonfatal major hemorrhagic events in patients with AF recurrence who continued on warfarin, but no hemorrhagic events were observed in patients free from AF (P = 0.002). CONCLUSIONS: Maintenance of sinus rhythm after catheter ablation of AF was associated with a lower incidence of thromboembolic events during long-term follow-up >3 years. This result suggests that catheter ablation reduces thromboembolic events if patients continue anticoagulation regardless of the ablation outcome. |
| | |
Authors:
|
Atsuhiko Yagishita; Yoshihide Takahashi; Atsushi Takahashi; Akira Fujii; Shigeki Kusa; Tadashi Fujino; Toshihiro Nozato; Taishi Kuwahara; Kenzo Hirao; Mitsuaki Isobe |
Related Documents
:
|
21829025 - Oral branched-chain amino acid granules reduce the incidence of hepatocellular carcinom... 18342545 - Interposition arthroplasty of the elbow with hinged external fixation for post-traumati... 21979395 - Inclusion of a spasmolytic in bowel cleansing: a prospective randomized study. 2133625 - Soft tissue calcification treated with local and oral magnesium therapy. 14709575 - National use of postmenopausal hormone therapy: annual trends and response to recent ev... 21829025 - Oral branched-chain amino acid granules reduce the incidence of hepatocellular carcinom... |
Publication Detail:
|
Type: Journal Article Date: 2011-07-21 |
Journal Detail:
|
Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 75 ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-09-22 Completed Date: 2012-03-13 Revised Date: 2012-12-19 |
Medline Journal Info:
|
Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
|
Languages: eng Pagination: 2343-9 Citation Subset: IM |
Affiliation:
|
Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Tokyo, Japan. atsuhikoyagishita@nifty.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Anticoagulants / therapeutic use Atrial Fibrillation / complications*, surgery Catheter Ablation* Female Follow-Up Studies Hemorrhage Humans Incidence Male Middle Aged Recurrence Thromboembolism / etiology*, prevention & control Warfarin / therapeutic use Young Adult |
| Chemical | |
Reg. No./Substance:
|
0/Anticoagulants; 81-81-2/Warfarin |
| Comments/Corrections | |
Comment In:
|
Circ J. 2011;75(10):2312-3
[PMID:
21817808
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Coronary calcium score as a predictor for coronary artery disease and cardiac events in Japanese hig...
Next Document: Diacylglycerol kinase ? inhibits ventricular tachyarrhythmias in a mouse model of heart failure.