| Incidence of Cryptosporidium in all patients submitting stool specimens for ova and parasite examination: monoclonal antibody IFA method. | |
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MedLine Citation:
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PMID: 3064957 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The development of a monoclonal antibody to Cryptosporidium oocysts provides a more sensitive detection method than that seen using other diagnostic techniques. Incidence reports on this organism have been based on earlier, less-sensitive methods. In order to determine the numbers of positive patients and stool specimens, every stool specimen submitted for an ova and parasite examination was tested using the Merifluor IFA system (Meridian Diagnostics, Inc). Over a 12-mo period, 2,786 specimens were tested (1,516 patients). Positive specimens (23) were from nine known immunosuppressed patients and from four symptomatic immunocompetent patients. This represents an overall positive rate of 0.86% (patients). In those patients who were not suspected of having cryptosporidiosis (immunocompetent), diagnosis of this infection would not have been accomplished without the use of a sensitive screening method. This data, obtained over a 12-mo period, provides information for those laboratories considering the clinical relevance of screening all stool specimens for this infection. With the development of therapy, early detection of Cryptosporidium will become more important. |
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Authors:
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L S Garcia; T C Brewer; D A Bruckner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Diagnostic microbiology and infectious disease Volume: 11 ISSN: 0732-8893 ISO Abbreviation: Diagn. Microbiol. Infect. Dis. Publication Date: 1988 Sep |
Date Detail:
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Created Date: 1989-03-16 Completed Date: 1989-03-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8305899 Medline TA: Diagn Microbiol Infect Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 25-7 Citation Subset: IM |
Affiliation:
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UCLA Medical Center 90024-1713. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antibodies, Monoclonal / diagnostic use Coccidia / isolation & purification* Cryptosporidiosis / epidemiology* Cryptosporidium / isolation & purification* Feces / parasitology Fluorescent Antibody Technique Humans Immunologic Deficiency Syndromes / complications Parasite Egg Count |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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