Document Detail

Inaugural Cerebral Sinovenous Thrombosis Revealing Homocystinuria in a 2-Year-Old Boy.
MedLine Citation:
PMID:  24598125     Owner:  NLM     Status:  Publisher    
Cerebral sinovenous thrombosis is unusual during childhood and requires early and accurate management because of its detrimental consequences. We report on the case of a 2-year-old boy with mild psychomotor delay, who presented with nonfebrile acute ataxia. A brain computed tomographic (CT) scan showed complete thrombosis of the superior sagittal sinus, confirmed by magnetic resonance angiography and associated with a right frontal hemorrhagic infarction. Systematic screening for thrombophilia revealed homocystinuria linked to cystathionine β-synthase deficiency with underlying compound heterozygosity. The evolution was favorable after anticoagulant therapy, specific diet, and vitamin supplementation. This case is of interest because of the unusual clinical presentation as a pediatric cerebral sinovenous thrombosis. Furthermore, homocystinuria is rarely revealed by cerebral sinovenous thrombosis at the onset of the disease and should systematically be ruled out in pediatric stroke.
Cécile Saboul; Stéphane Darteyre; Cécile Ged; Christine Fichtner; Claire Gay; Jean-Louis Stephan
Related Documents :
20189075 - Imaging findings of femoroacetabular impingement syndrome: focusing on mixed-type impin...
9677645 - Mr imaging of hyaline cartilage at 0.5 t: a quantitative and qualitative in vitro evalu...
16846765 - Advanced magnetic resonance imaging of articular cartilage.
15995425 - Patellofemoral joint biomechanics and tissue engineering.
14617375 - Correlations from gadopentetate dimeglumine-enhanced magnetic resonance imaging after m...
16890665 - 11c-choline positron emission tomography/computerized tomography for tumor localization...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-3-5
Journal Detail:
Title:  Journal of child neurology     Volume:  -     ISSN:  1708-8283     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-3-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparison of small interfering RNA (siRNA) delivery into bovine monocyte-derived macrophages by tra...
Next Document:  Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial t...