Document Detail

Inappropriate use of potent topical glucocorticoids in infants.
MedLine Citation:
PMID:  17396439     Owner:  NLM     Status:  MEDLINE    
Topical therapy with glucocorticoids (GCs) is used commonly in chronic dermatoses. Side effects are less common compared to systemic use; however, newer potent preparations may have serious side effects. A potential danger is their inappropriate use. Three infants who developed iatrogenic Cushing's syndrome and prolonged adrenal suppression in the course of GC therapy for simple diaper dermatitis are described. One patient also developed steatohepatitis which is uncommon with local GCs.
Alev Ozon; Semra Cetinkaya; Ayfer Alikasifoglu; E Nazli Gonc; Yaşar Sen; Nurgün Kandemir
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  20     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-04-02     Completed Date:  2007-04-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  219-25     Citation Subset:  IM    
Department of Pediatrics, Division of Endocrinology, Medical Faculty, Hacettepe University, Ihsan Dogramaci Children's Hospital, Ankara, Turkey.
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MeSH Terms
Administration, Topical
Cushing Syndrome / chemically induced*,  diagnosis
Dermatitis / drug therapy*
Diagnosis, Differential
Fatty Liver / chemically induced,  diagnosis
Glucocorticoids / administration & dosage,  adverse effects*,  contraindications
Hypothalamo-Hypophyseal System / drug effects,  physiopathology
Iatrogenic Disease
Obesity / diagnosis
Pituitary-Adrenal System / drug effects,  physiopathology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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