| Inappropriate secretion of antidiuretic hormone treated with frusemide. | |
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MedLine Citation:
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PMID: 6805839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Seven out of nine patients with chronic inappropriate secretion of antidiuretic hormone were successfully treated with 40 mg frusemide daily. One patient needed 80 mg, and the remaining patient achieved only a small increase in diuresis after 40 mg frusemide; this was probably related to his low creatinine clearance. In order to maintain a salt intake high enough to compensate for the loss of urine electrolytes 3 to 6 g sodium chloride was added as tablets to the sodium-free diet in six patients. Hypokalaemia occurred in five patients but was easily corrected with either supplements of potassium chloride or a potassium-sparing diuretic. These findings add further weight to evidence that Frusemide is a good alternative for the treatment of patients with inappropriate secretion of antidiuretic hormone who cannot tolerate water restriction. |
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Authors:
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G Decaux; Y Waterlot; F Genette; R Hallemans; J C Demanet |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British medical journal (Clinical research ed.) Volume: 285 ISSN: 0267-0623 ISO Abbreviation: Br Med J (Clin Res Ed) Publication Date: 1982 Jul |
Date Detail:
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Created Date: 1982-08-26 Completed Date: 1982-08-26 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 8302911 Medline TA: Br Med J (Clin Res Ed) Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 89-90 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chronic Disease Furosemide / therapeutic use* Humans Inappropriate ADH Syndrome / drug therapy* Sodium Chloride / therapeutic use |
| Chemical | |
Reg. No./Substance:
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54-31-9/Furosemide; 7647-14-5/Sodium Chloride |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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