Document Detail

Inappropriate secretion of antidiuretic hormone in a patient with chronic inflammatory demyelinating polyneuropathy.
MedLine Citation:
PMID:  15704666     Owner:  NLM     Status:  MEDLINE    
A 54-year-old man suffered from a relapse of chronic inflammatory demyelinating polyneuropathy (CIDP), and developed quadriplegia and somnolence requiring mechanical ventilation for respiratory failure. Serum Na concentration remained at low levels during the clinical course, and a diagnosis of inappropriate secretion of antidiuretic hormone (SIADH) was made. The present case had not only acute aggravation of CIDP with autonomic dysfunction but also intracranial hypertension caused by increased CSF protein (maximum level, 1,315 mg/dl). It seemed likely that injury of the afferent fibers of the baroregulatory pathway or intracranial hypertension might have contributed to SIADH in this patient.
Yoshiharu Taguchi; Shutaro Takashima; Etsuko Sasahara; Yoichi Kato; Tadaaki Orihara; Yukichi Inoue; Hiroshi Inoue
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  44     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-02-11     Completed Date:  2005-05-03     Revised Date:  2005-11-01    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  65-7     Citation Subset:  IM    
Second Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Toyama.
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MeSH Terms
Immunoglobulins, Intravenous / therapeutic use
Inappropriate ADH Syndrome / etiology*,  physiopathology
Middle Aged
Neural Conduction / physiology
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / complications*,  diagnosis,  drug therapy
Respiration, Artificial
Reg. No./Substance:
0/Immunoglobulins, Intravenous
Comment In:
Intern Med. 2005 Jul;44(7):685-6   [PMID:  16093583 ]

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