| Inadequate vitamin D status in pregnancy: evidence for supplementation. | |
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MedLine Citation:
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PMID: 22007763 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The role of vitamin D in maintaining a healthy pregnancy has seen emerging interest amongst clinicians and researchers in recent years. The functions of this hormone are widespread and complex and during pregnancy and breastfeeding it facilitates crucial transfer of calcium from mother to child for skeletal development. Aside from the role of vitamin D in bone development and health, a myriad of other physiological actions are now known, and it is hypothesised that maternal deficiency may increase susceptibility to adverse pregnancy events during pregnancy such as pre-eclampsia. The role of vitamin D in pregnancy and breastfeeding is summarised and applied to the knowledge from studies associating vitamin D deficiency with a range of adverse pregnancy outcomes, including pre-eclampsia and childhood asthma. Current clinical guidelines for vitamin D supplementation in pregnancy are discussed in the context of the available evidence. The need for robust randomised controlled trials to address areas of existing uncertainty is highlighted. |
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Authors:
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Sarah Finer; Khalid S Khan; Graham A Hitman; Chris Griffiths; Adrian Martineau; Catherine Meads |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-18 |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: - ISSN: 1600-0412 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 The Authors AOGS© 2011 Nordic Federation of Societies of Obstetrics and Gynecology. |
Affiliation:
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Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London. UK. |
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