| Inadequate treatment of syphilis in pregnancy. | |
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MedLine Citation:
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PMID: 6507531 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pregnant women with untreated syphilis have high rates of adverse pregnancy outcome. Early syphilis in pregnancy, if not treated, results in 40% loss either by spontaneous abortions, stillbirth, or perinatal death. Another 40% of such pregnancies result in an infant born with congenital syphilis. Only 20% of such pregnancies result in a normal infant. Currently recommended treatment of early syphilis in pregnant women uses a dosage of 2.4 million U of benzathine penicillin G. Because of the potentially disastrous effect syphilis has on pregnancy outcome, the occurrence of any treatment failure must be considered seriously. In this brief report we present clinical summaries of four pregnant women treated for syphilis who represent probable treatment failures. |
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Authors:
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L Mascola; R Pelosi; C E Alexander |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 150 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1984 Dec |
Date Detail:
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Created Date: 1985-01-15 Completed Date: 1985-01-15 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 945-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Fetal Death / etiology Humans Infant, Newborn Infant, Premature, Diseases / diagnosis Penicillin G / therapeutic use* Penicillin G Benzathine / administration & dosage, therapeutic use* Pregnancy Pregnancy Complications / drug therapy* Syphilis / drug therapy* Syphilis Serodiagnosis Syphilis, Congenital / diagnosis, drug therapy Syphilis, Latent / diagnosis, drug therapy |
| Chemical | |
Reg. No./Substance:
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1538-09-6/Penicillin G Benzathine; 61-33-6/Penicillin G |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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