Document Detail


Inadequate cerebral oxygen delivery and central fatigue during strenuous exercise.
MedLine Citation:
PMID:  17620929     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Under resting conditions, the brain is protected against hypoxia because cerebral blood flow increases when the arterial oxygen tension becomes low. However, during strenuous exercise, hyperventilation lowers the arterial carbon dioxide tension and blunts the increase in cerebral blood flow, which can lead to an inadequate oxygen delivery to the brain and contribute to the development of fatigue.
Authors:
Lars Nybo; Peter Rasmussen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Exercise and sport sciences reviews     Volume:  35     ISSN:  0091-6331     ISO Abbreviation:  Exerc Sport Sci Rev     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-07-10     Completed Date:  2007-09-06     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0375434     Medline TA:  Exerc Sport Sci Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  110-8     Citation Subset:  IM    
Affiliation:
Institute of Exercise and Sport Sciences and Department of Anaesthesia, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. lnnielsen@aki.ku.dk
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MeSH Terms
Descriptor/Qualifier:
Anoxia / etiology*,  metabolism
Brain / blood supply*
Central Nervous System
Denmark
Exercise / physiology*
Fatigue / etiology
Humans
Mitochondria
Oxygen Consumption / physiology
Physical Exertion / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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