| Inactivity, exercise, and visceral fat. STRRIDE: a randomized, controlled study of exercise intensity and amount. | |
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MedLine Citation:
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PMID: 16002776 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite the importance of randomized, dose-response studies for proper evaluation of effective clinical interventions, there have been no dose-response studies on the effects of exercise amount on abdominal obesity, a major risk factor for metabolic syndrome, diabetes, and cardiovascular disease. One hundred seventy-five sedentary, overweight men and women with mild to moderate dyslipidemia were randomly assigned to participate for 6 mo in a control group or for approximately 8 mo in one of three exercise groups: 1) low amount, moderate intensity, equivalent to walking 12 miles/wk (19.2 km) at 40-55% of peak oxygen consumption; 2) low amount, vigorous intensity, equivalent to jogging 12 miles/wk at 65-80% of peak oxygen consumption; or 3) high amount, vigorous intensity, equivalent to jogging 20 miles/wk (32.0 km). Computed tomography scans were analyzed for abdominal fat. Controls gained visceral fat (8.6 +/- 17.2%; P = 0.001). The equivalent of 11 miles of exercise per week, at either intensity, prevented significant accumulation of visceral fat. The highest amount of exercise resulted in decreased visceral (-6.9 +/- 20.8%; P = 0.038) and subcutaneous (-7.0 +/- 10.8%; P < 0.001) abdominal fat. Significant gains in visceral fat over only 6 mo emphasize the high cost of continued inactivity. A modest exercise program, consistent with recommendations from the Centers for Disease Control/American College of Sports Medicine (CDC/ACSM), prevented significant increases in visceral fat. Importantly, a modest increase over the CDC/ACSM exercise recommendations resulted in significant decreases in visceral, subcutaneous, and total abdominal fat without changes in caloric intake. |
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Authors:
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Cris A Slentz; Lori B Aiken; Joseph A Houmard; Connie W Bales; Johanna L Johnson; Charles J Tanner; Brian D Duscha; William E Kraus |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2005-07-07 |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 99 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-09-14 Completed Date: 2005-12-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: United States |
Other Details:
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Languages: eng Pagination: 1613-8 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Fat
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radiography* Adipose Tissue / radiography* Adult Dyslipidemias / radiography* Energy Intake Exercise* Female Humans Male Middle Aged Oxygen Consumption Rest Risk Reduction Behavior Running Subcutaneous Tissue* Time Factors Tomography, X-Ray Computed Viscera* Walking |
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