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Inactivation of Shiga Toxin-Producing Escherichia coli (STEC) and Degradation/Removal of Cellulose from STEC Surfaces Using Selected Enzymatic and Chemical Treatments.
MedLine Citation:
PMID:  22003030     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Some Shiga toxin-producing E. coli (STEC) produce extracellular cellulose, a long polymer of glucose with β-1-4 glycosidic bonds. This study evaluated the efficacies of selected enzymatic and chemical treatments in inactivating STEC and degrading/removing the cellulose on STEC surfaces. Six cellulose-producing STEC were treated with cellulase (0.51 to 3.83 U/15 ml), acetic and lactic acid (2 and 4%), as well as an acidic and alkaline sanitizer (manufacturer recommended concentrations), respectively under appropriate conditions. Following each treatment, residual amounts of cellulose and surviving populations of STEC were determined. Treatments with acetic and lactic acid significantly reduced (P < 0.05) the populations of STEC, and those with lactic acid also significantly decreased the amounts of cellulose on STEC. The residual amounts of cellulose on STEC positively correlated to the surviving populations of STEC after the treatments with the organic acids (r = 0.64-0.94), and significance of the correlations ranged from 83 to 99%. Treatments with cellulase and the sanitizers both degraded cellulose. However, treatments with cellulase had no influence on the fate of STEC, and those with the sanitizers reduced STEC cell populations to undetectable levels. Thus, the correlations between the residual amounts of cellulose and the surviving populations of STEC caused by these two treatments were not observed. Results suggest that the selected enzymatic and chemical agents degraded/removed the cellulose on STEC surfaces, and the treatments with organic acids and sanitizers also inactivated STEC cells. The amounts of cellulose produced by STEC appear to affect their susceptibilities to certain sanitizing treatments.
Authors:
Yoen Ju Park; Jinru Chen
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-14
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  -     ISSN:  1098-5336     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Food Science and Technology, The University of Georgia, 1109 Experiment Street, Griffin, GA 30223-1797 USA.
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