Document Detail


Inactivation of Ascaris suum by short-chain fatty acids.
MedLine Citation:
PMID:  21057018     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ascaris suum eggs were inactivated in distilled water and digested sludge by butanoic, pentanoic, and hexanoic acids. The fatty acids (short-chain fatty acids [SCFA]) were effective only when protonated and at sufficient concentrations. The conjugate bases were not effective at the concentrations evaluated. Predictions from an inhibition model (50% inhibitory concentration [IC(50)]) based on quantitative structure-activity relationships were congruent with inactivation data.
Authors:
Michael A Butkus; Kelly T Hughes; Dwight D Bowman; Janice L Liotta; Michael B Jenkins; Michael P Labare
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-11-05
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  77     ISSN:  1098-5336     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-23     Completed Date:  2011-03-15     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  363-6     Citation Subset:  IM    
Affiliation:
Department of Geography and Environmental Engineering, US Military Academy, West Point, New York 10996, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anthelmintics / pharmacology*
Ascaris suum / drug effects*
Butyrates / pharmacology*
Caproates / pharmacology*
Inhibitory Concentration 50
Pentanoic Acids / pharmacology*
Chemical
Reg. No./Substance:
0/Anthelmintics; 0/Butyrates; 0/Caproates; 0/Pentanoic Acids; 142-62-1/hexanoic acid
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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