Document Detail

Inaccuracy of cytologic diagnosis in high grade squamous intraepithelial lesions (CIN 3).
MedLine Citation:
PMID:  7847009     Owner:  NLM     Status:  MEDLINE    
Through a retrospective review of records, this study attempted to determine whether a correlation between cytology and histology would change with time in one laboratory. The study encompassed a geographic area of Scotland with a female population of 175,500 served by one colposcopy clinic, at Ninewells Hospital and Medical School, Dundee. The subjects were referred to the Nine-wells colposcopy clinic between January 1, 1985, and December 31, 1990. The results showed many women with high grade squamous intraepithelial lesions (SILs) (CIN 3) and cytology revealing abnormalities milder than severe dyskaryosis, for an average of 71.9% over the six years of the study. The referral of women for colposcopic assessment if they have persistent smears showing mild dyskaryosis suggestive of low grade SILs seems to be worthwhile.
H Lyall; I D Duncan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  39     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1995 Jan-Feb
Date Detail:
Created Date:  1995-03-06     Completed Date:  1995-03-06     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  50-4     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, University of Dundee, Scotland.
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MeSH Terms
Biopsy, Needle
Carcinoma in Situ / diagnosis*,  epidemiology,  pathology*
Carcinoma, Squamous Cell / diagnosis*,  epidemiology,  pathology*
Colposcopy / methods,  standards
Diagnostic Errors
Retrospective Studies
Scotland / epidemiology
Uterine Cervical Neoplasms / diagnosis*,  pathology*

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