Document Detail


In vivo ultrasonic measurement of tissue vibration at a stenosis: a case study.
MedLine Citation:
PMID:  11527591     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It is known that bruits often can be heard downstream from stenoses. They are thought to be produced by disturbed blood flow and vessel wall vibrations. Our understanding of bruits has been limited, though, to analysis of sounds heard at the level of the skin. For direct measurements from the stenosis site, we developed an ultrasonic pulse-echo multigate system using quadrature phase demodulation. The system simultaneously measures tissue displacements and blood velocities at multiple depths. This paper presents a case study of a severe stenosis in a human infrainguinal vein bypass graft. During systole, nearly sinusoidal vessel wall vibrations were detected. Solid tissue vibration amplitudes measured up to 2 microm, with temporal durations of 100 ms and frequencies of roughly 145 Hz and its harmonics. Cross-axial oscillations were also found in the lumen that correlate with the wall vibrations, suggesting coupling between wall vibration and blood velocity oscillation.
Authors:
M I Plett; K W Beach; B Dunmire; K G Brown; J F Primozich; E Strandness
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  27     ISSN:  0301-5629     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-08-30     Completed Date:  2001-10-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1049-58     Citation Subset:  IM    
Affiliation:
Department of Electrical Engineering, Seattle Pacific University, Seattle, WA 98119, USA. mplett@spu.edu
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MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Constriction, Pathologic / ultrasonography
Graft Occlusion, Vascular / ultrasonography
Humans
Peripheral Vascular Diseases / ultrasonography*
Vibration

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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