| In vivo total body water assessment by total body electrical conductivity in rats suffering perturbations of water compartment equilibrium. | |
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MedLine Citation:
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PMID: 8260470 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Total body electrical conductivity (TOBEC) is a simple and non-invasive method for the assessment of body composition in vivo. Information regarding the applicability of TOBEC in the condition of abnormal fluid balance is scarce. In the present paper we give the results of the comparison between TOBEC and total body water (TBW; assessed by the tritium dilution technique) in three groups of animals: (1) healthy (n 17), (2) expanded fluid volume by secondary biliary cirrhosis (SBC; n 9) and (3) Furosemide-treated rats (n 9). The TOBEC score and TBW by tritium dilution were found to be highly correlated in the pooled sample (r 0.90) and in normal (r 0.87), SBC (r 0.73) and Furosemide-treated (r 0.89) rats. However, the relationship between TOBEC and TBW, described by least-squares regression analysis, was found to be similar for SBC and normal rats but was significantly different for Furosemide-treated and normal rats. These findings suggest that TOBEC is unable to track TBW accurately when the ratio between intracellular and extracellular water is chronically or acutely altered. |
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Authors:
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N Battistini; F Virgili; G Bedogni; G R Gambella; A Bini |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The British journal of nutrition Volume: 70 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 1993 Sep |
Date Detail:
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Created Date: 1994-01-24 Completed Date: 1994-01-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 433-8 Citation Subset: IM |
Affiliation:
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Institute of Human Physiology and Pathology, University of Modena, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Composition Body Water / physiology* Electric Conductivity Extracellular Space / chemistry Furosemide Least-Squares Analysis Liver Cirrhosis, Biliary / metabolism Male Rats Rats, Sprague-Dawley Water-Electrolyte Imbalance / chemically induced, physiopathology* |
| Chemical | |
Reg. No./Substance:
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54-31-9/Furosemide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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