Document Detail

In vivo quantitative ultrasonic evaluation of neonatal brain with a real time integrated backscatter imaging system.
MedLine Citation:
PMID:  12907275     Owner:  NLM     Status:  MEDLINE    
We applied the integrated backscatter (IBS) imaging system to the evaluation of the normal neonatal brain of different birth-weights: extremely low-birth-weight (N=13), very-low-birth-weight (N=14), low-birth weight (N=14), and normal birth weight (N=19). The IBS values in six regions of interest, the deep white matter, subcortical white matter, choroid plexus, thalamus, lateral ventricle, and occipital bone, were compared among groups of different birth weights, gestational age, and postnatal age: at the date of birth and 28 approximately 30 days after birth. The IBS values were higher in the order of bone>choroid plexus>deep white matter>subcortical white matter>thalamus>lateral ventricle and were significantly different except for the lateral ventricle in all the groups at days 0 and 28 approximately 30. The IBS values increased with the decrease of birth weight and gestational age. There was a decrease of IBS values at day 28 compared to that of day 0 in the extremely low birth weight and very low birth weight groups; however, they remained the same in infants with low birth weights and in the normal birth weight group. Further studies to evaluate the significance of this technique for the objective diagnosis of brain insults in neonates are necessary.
Chizu Fujimoto; Yushiro Yamashita; Hiroshi Kanda; Eimei Harada; Yasuki Maeno; Toyojiro Matsuishi
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain & development     Volume:  25     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-08     Completed Date:  2003-10-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  411-5     Citation Subset:  IM    
Department of Pediatrics and Child Health, Kurume University School of Medicine, 67 Asahi-machi, Kurume-city, Fukuoka 830-0011, Japan.
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MeSH Terms
Age Factors
Brain / anatomy & histology*,  growth & development*
Gestational Age
Infant, Low Birth Weight / physiology
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight / physiology
Ultrasonography* / methods

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