| In vivo protective effect of dietary curcumin in fish Anabas testudineus (Bloch). | |
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MedLine Citation:
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PMID: 21604159 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The present study describes, for the first time, the protective effect of natural curcumin in vivo in a lower vertebrate, a teleost, Anabas testudineus (Bloch). Two doses of curcumin 0.5 and 1% were supplemented in the 40% protein feed and fed to fish for the periods, 2 and 8 weeks. The antioxidant status, protein content, and the tissue structure in experimental fish were examined after the short-term and long-term feeding. In all the curcumin fed groups, the lipid peroxidation product, thiobarbituric acid reactive substances content either decreased or unaffected. The glutathione content increased while the antioxidant enzyme activity pattern varied with time and dose. The histological analysis also confirmed the safety of curcumin retaining the normal arrangement of hepatocytes, hepatopancreas, macrophage-melanocyte centers in Anabas. The improved antioxidant status and protein content suggest a favorable effect for curcumin in cultured fish. |
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Authors:
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Maniyan Manju; Mohammad Abdulkader Akbarsha; Oommen Vilaverthottathil Oommen |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-22 |
Journal Detail:
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Title: Fish physiology and biochemistry Volume: - ISSN: 1573-5168 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100955049 Medline TA: Fish Physiol Biochem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Zoology, University of Kerala, Kariavattom, Thiruvananthapuram, 695581, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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