Document Detail


In vivo production of thromboxane in acute human myocardial infarction: a preliminary study.
MedLine Citation:
PMID:  3992528     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using a specific quantitative method based on gas chromatography-mass spectrometry the urinary excretion of 2,3-dinor-TxB2 was measured in five patients with acute myocardial infarction shortly after the onset of symptoms. The urinary excretion of 2,3-dinor-TxB2 was markedly higher than seen in normals in three of the five patients. This increased excretion of 2,3-dinor-TxB2 during and after the development of myocardial necrosis indicates an involvement of thromboxane A2 in the pathogenesis of at least some cases of acute myocardial infarction.
Authors:
O Vesterqvist; O Edhag; K Green; P Henriksson
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Thrombosis research     Volume:  37     ISSN:  0049-3848     ISO Abbreviation:  Thromb. Res.     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-06-10     Completed Date:  1985-06-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0326377     Medline TA:  Thromb Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  459-64     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Female
Gas Chromatography-Mass Spectrometry
Humans
Kinetics
Male
Middle Aged
Myocardial Infarction / urine*
Thromboxane A2 / biosynthesis*
Thromboxane B2 / analogs & derivatives,  urine*
Thromboxanes / biosynthesis*,  urine*
Chemical
Reg. No./Substance:
0/Thromboxanes; 54397-85-2/Thromboxane B2; 57576-52-0/Thromboxane A2; 63250-09-9/2,3-dinor-thromboxane B2

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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