Document Detail

In vivo observation of magnified features of pigmented lesions on volar skin using video macroscope. Usefulness of epiluminescence techniques in clinical diagnosis.
MedLine Citation:
PMID:  7887659     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND DESIGN: In vivo epiluminescence microscopy is now used as a useful noninvasive method for determining clinical diagnosis of pigmented skin lesions. Until now, however, pigmented lesions on the volar skin have been hardly studied with this method. In the present epiluminescent study, various kinds of pigmented lesions on the volar skin were extensively investigated by means of video macroscope, a newly developed electronic device with a higher magnification power, and correlation between the magnified features and histopathologic findings was evaluated. RESULTS: Magnified features of most lesions of acquired or congenital melanocytic nevus on the volar skin were classified into the following three typical patterns: (1) a parallel pattern formed by pigmented parallel lines corresponding to the furrows of the skin markings, (2) a latticelike pattern composed of pigmented lines along and across the furrows of the skin markings, and (3) a fibrillar pattern formed by densely packed, fibrillar pigmented lines arranged in the direction crossing the furrows. In contrast, macular or plaque portions of acral lentiginous melanoma exhibited disorderly arranged, irregular pigment patterns, mainly affecting the ridges of the skin markings. In addition, brown globules of various shades and many black dots of variable sizes were often observed and, on the margin of the lesions, pseudopods and/or the "serrated" pattern were detected. Cutaneous hemorrhagic macule and so-called black heel showed highly specific features and thus could be easily diagnosed with video macroscopy. CONCLUSION: Video macroscope proved to be a very useful instrument for the diagnosis of pigmented lesions on the volar skin.
T Saida; S Oguchi; Y Ishihara
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of dermatology     Volume:  131     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1995 Mar 
Date Detail:
Created Date:  1995-04-07     Completed Date:  1995-04-07     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  298-304     Citation Subset:  AIM; IM    
Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.
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MeSH Terms
Equipment Design
Foot Dermatoses / pathology*
Hand Dermatoses / pathology*
Light / diagnostic use*
Melanoma / pathology*
Nevus, Pigmented / pathology*
Pigmentation Disorders / pathology*
Skin Neoplasms / pathology*
Video Recording*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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