Document Detail


In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T.
MedLine Citation:
PMID:  17661098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECT: To evaluate the feasibility of mouse spinal cord MR imaging using echo-planar imaging (EPI). MATERIALS AND METHODS: Optimized multi-shot spin-echo-EPI sequences were compared to conventional spin-echo (c-SE) at 11.75 T and used for high-spatially resolved acquisitions and relaxation-time measurements. RESULTS: Good quality images were obtained, with clear delineation of gray and white matter. Acquisition-time gain factor was up to 6 (vs. c-SE) and resolution up to 74 x 94 microm2 was achieved. T1 and T2 relaxation times were reliably measured. CONCLUSION: High-temporally and spatially resolved mouse spinal cord EPI imaging is feasible. This technique should greatly benefit to long acquisition-time experiments (diffusion imaging) and imaging of rapidly-evolving pathologies.
Authors:
Virginie Callot; Guillaume Duhamel; Patrick J Cozzone
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Publication Detail:
Type:  Journal Article     Date:  2007-07-28
Journal Detail:
Title:  Magma (New York, N.Y.)     Volume:  20     ISSN:  0968-5243     ISO Abbreviation:  MAGMA     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-11-13     Completed Date:  2008-01-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9310752     Medline TA:  MAGMA     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  169-73     Citation Subset:  IM    
Affiliation:
Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR CNRS, Faculté de Médecine de Marseille, Université de la Méditerranée, 27 Bd Jean Moulin, 13385, Marseille Cedex 5, France. virginie.callot@medecine.univ-mrs.fr
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MeSH Terms
Descriptor/Qualifier:
Animals
Echo-Planar Imaging / methods*
Mice
Reproducibility of Results
Sensitivity and Specificity
Spinal Cord / anatomy & histology*

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