Document Detail

In vivo extracellular recording of sympathetic ganglion activity in a chronic animal model.
MedLine Citation:
PMID:  14673682     Owner:  NLM     Status:  MEDLINE    
Surgery of the sympathetic system is performed for a variety of indications, hyperhidrosis being a major one. Despite excellent results, sympathectomy for hyperhidrosis bears a number of sequels, some of which may be devastating. Several surgical methods, empirically advocated to alleviate these problems, have only limited success. Chronic in vivo recording of the electrical activity from sympathetic ganglia may assist in understanding and clarifying complex problems of sympathetic surgery; however, no suitable method has been reported. An electrode device developed by our group was implanted on the stellate ganglion, in a chronic animal model (dog). The signals obtained were amplified, filtered, and transmitted via an A/D interface to be acquired and saved on a computer, using special software which we developed. Our method enabled the separate recording of neuroelectrical signals, ECG, and respiration waves. An additional software program, also developed by our group, was used to analyze the data. This chronic animal model allows investigation of surgical and pharmacological manipulations of the sympathetic system.
Gila Lavian; Doron Kopelman; Avshalom Shenhav; Eugene Konyukhov; Urit Gardi; Asaph Zaretzky; Rona Shofti; John P M Finberg; Moshe Hashmonai
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical autonomic research : official journal of the Clinical Autonomic Research Society     Volume:  13 Suppl 1     ISSN:  0959-9851     ISO Abbreviation:  Clin. Auton. Res.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-15     Completed Date:  2004-09-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9106549     Medline TA:  Clin Auton Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  I83-8     Citation Subset:  IM    
Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
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MeSH Terms
Automatic Data Processing
Electrodes, Implanted*
Electrophysiology / instrumentation
Equipment Design
Extracellular Fluid / physiology*
Ganglia, Sympathetic / physiology*
Models, Animal*
Respiratory Physiological Phenomena
Stellate Ganglion / physiology*,  surgery
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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