Document Detail


In vivo evaluation of tissue microflow under combined therapy with extracorporeal life support and intra-aortic balloon counterpulsation.
MedLine Citation:
PMID:  19775051     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Treatment with percutaneous extracorporeal mechanical assist devices provides the ultimate therapeutic option to improve the macrocirculation in patients suffering from refractory cardiac arrest, severe cardiogenic shock or during high-risk interventions. However, the flow in the smallest vessels in these critical periods is poorly understood but prognostically of high importance. Using sidestream darkfield intravitalmicroscopy, we visualised the sublingual microflow in a patient suffering from severe cardiogenic shock supported by extracorporeal membrane oxygenation and intra-aortic balloon pump. Our results show that intra-aortic balloon counterpulsation applied in addition to extracorporeal membrane oxygenation further improves the microflow. This in vivo finding supports pilot studies favouring the application of devices supporting cardiac output (extracorporeal membrane oxygenation) together with devices aimed at pulsatility (intra-aortic balloon pump).
Authors:
C Jung; A Lauten; C Roediger; M Fritzenwanger; J Schumm; H R Figulla; M Ferrari
Publication Detail:
Type:  Case Reports; Evaluation Studies; Journal Article    
Journal Detail:
Title:  Anaesthesia and intensive care     Volume:  37     ISSN:  0310-057X     ISO Abbreviation:  Anaesth Intensive Care     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-24     Completed Date:  2010-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0342017     Medline TA:  Anaesth Intensive Care     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  833-5     Citation Subset:  IM    
Affiliation:
Division of Cardiology, Department of Internal Medicine I, Friedrich-Schiller-University, Jena, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Equipment Design
Extracorporeal Membrane Oxygenation / methods*
Fatal Outcome
Female
Humans
Intra-Aortic Balloon Pumping / methods*
Microcirculation*
Mouth Floor / blood supply
Shock, Cardiogenic / therapy*
Comments/Corrections
Comment In:
Anaesth Intensive Care. 2009 Sep;37(5):700-2   [PMID:  19775031 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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