Document Detail


In vivo documentation of an arteriovenous shunt in rat pancreatic acinar tissue.
MedLine Citation:
PMID:  8829179     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
With the use of epiilumination fluorescence microscopy, we demonstrate for the first time in vivo the existence and function of direct arteriovenous communication (arteriovenous shunt) in rat pancreatic acinar tissue. In eight Sprague-Dawley rats the corpus and tail of the pancreatic gland were reviewed for arteriovenous anastomoses. In seven animals the technique did not allow us to visualize completely the arteriolar and venular vascular system due to overlying pancreatic tissue. In one animal, however, the vascular trees could be identified in their continuity over a length of several millimeters, including an arteriovenous shunt with a diameter of 12.0 microns. Analysis of volumetric blood flow revealed that 86.2% (15.61 nl/min) of the arteriolar blood volume was shunted into the venule, while only 13.8% (2.50 nl/min) of the blood volume was carried by the arteriole distal to the arteriovenous shunt to the nutritive capillary bed. There were no changes in diameter, i.e., vasoconstriction, vasodilation, or vasomotion, over an observation period of 30 min, indicating that, at least under physiological conditions, this arteriovenous communication functioned as a real "fare-through" channel.
Authors:
M D Menger; B Vollmar
Related Documents :
24328019 - A comparative study of methylergonovine and 15-methyl prostaglandin f2α in active manag...
10919259 - Islet blood flow in multiple low dose streptozotocin-treated wild-type and inducible ni...
474769 - Cardiac lymph flow in conscious dogs.
24902619 - In-utero sensitization modulates igg isotype, ifn-γ and il-10 responses of neonates in ...
24113499 - Rheological parameters in the umbilical cord blood in moderate and severe forms of pree...
892689 - Effect on pancreatic blood flow and insulin output of infusions of aminophylline, galac...
22632889 - The physician compliance of red blood cell transfusion by computerized transfusion deci...
8418019 - Calcium dependence of flow-induced dilation. cooperative interaction with sodium.
1253189 - Effects of drugs on the negative (backflow) component of velocity patterns in the dog a...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pancreas     Volume:  13     ISSN:  0885-3177     ISO Abbreviation:  Pancreas     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-12-06     Completed Date:  1996-12-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8608542     Medline TA:  Pancreas     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  125-9     Citation Subset:  IM    
Affiliation:
Institute for Clincal & Experimental Surgery, University of Saarland, Homburg/Saar, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Arterioles / anatomy & histology,  physiology
Arteriovenous Anastomosis / anatomy & histology*
Blood Flow Velocity
Fluorescein-5-isothiocyanate
Fluorescent Dyes
Male
Microscopy, Fluorescence / methods
Pancreas / blood supply*
Rats
Rats, Sprague-Dawley
Vasoconstriction
Vasodilation
Venules / anatomy & histology,  physiology
Chemical
Reg. No./Substance:
0/Fluorescent Dyes; 3326-32-7/Fluorescein-5-isothiocyanate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cat pancreatic neurons: morphology, electrophysiological properties, and responses to 5-HT.
Next Document:  Relationship between native and recombinant cholecystokinin receptors: role of differential glycosyl...