Document Detail

In vivo comparison of lumen dimensions measured by time domain-, and frequency domain-optical coherence tomography, and intravascular ultrasound.
MedLine Citation:
PMID:  23292151     Owner:  NLM     Status:  Publisher    
Lumen dimensions measured by time-domain optical coherence tomography (TD-OCT) may be influenced by the hemodynamic effect of proximal balloon occlusion. Frequency-domain OCT (FD-OCT) does not require the interruption of blood flow. Therefore, we compared the coronary lumen dimensions measured by TD-OCT, FD-OCT, and intravascular ultrasound (IVUS) in both stented and non-stented segments. Twenty patients who underwent both IVUS and OCT imaging (10 for TD- and 10 for FD-OCT) after stent implantation were included. The maximum, minimum, and mean diameters and areas were measured at the proximal and distal stent edges, as well as 3 mm inside and 5 mm outside of both edges. The measurements inside stent showed no significant differences between IVUS and TD- or FD-OCT. The lumen mean diameters and areas measured by IVUS at 5 mm outside stent were similar to those measured by FD-OCT (Distal; 3.07 ± 0.7 vs 3.03 ± 0.7 mm, p = 0.08 and 7.80 ± 4.0 vs 7.72 ± 4.1 mm(2), p = 0.07, respectively. Proximal; 3.25 ± 0.7 vs 3.23 ± 0.7 mm, p = 0.09 and 8.78 ± 3.8 vs 8.65 ± 3.7 mm(2), p = 0.08, respectively), but were greater than those measured by TD-OCT (Distal; 2.75 ± 0.5 vs 2.29 ± 0.5 mm, p = 0.0001 and 6.15 ± 2.6 vs 4.38 ± 1.9 mm(2), p = 0.0002, respectively. Proximal; 3.27 ± 0.6 vs 2.69 ± 0.6 mm, p = 0.0001 and 8.64 ± 3.4 vs 6.12 ± 2.7 mm(2), p = 0.0001 respectively). The interaction between TD- and FD-OCT for lumen dimension measurements at 5 mm outside stent was statistically significant. Vessel dimension measurements were similar between IVUS and FD-OCT in native vessel unlike with TD-OCT. Therefore, we might adapt the IVUS criteria of lesion severity for percutaneous coronary intervention to FD-OCT.
Soo-Joong Kim; Hang Lee; Koji Kato; Taishi Yonetsu; Ik-Kyung Jang
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-6
Journal Detail:
Title:  The international journal of cardiovascular imaging     Volume:  -     ISSN:  1875-8312     ISO Abbreviation:  Int J Cardiovasc Imaging     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100969716     Medline TA:  Int J Cardiovasc Imaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Cardiology Division, Massachusetts General Hospital, Harvard Medical School, GRB 800, 55 Fruit Street, Boston, MA, USA.
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