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In vivo comparison between laser-treated and grit blasted/acid etched titanium.
MedLine Citation:
PMID:  23346926     Owner:  NLM     Status:  Publisher    
OBJECTIVE: Laser profiling of titanium has been of considerable interest in the field of oral implantology. However, very few pre-clinical and clinical studies have been performed with laser-treated implants, especially focusing on isotropic roughness topography. The aim of the study was to compare the cortical bone response of Ti-implants discs treated with pico-sec pulsed laser (LAS) and conventional grit-blasted/acid-etched (GAE) method. MATERIALS AND METHODS: Prior to the in vivo experiment, in vitro cell viability testing of the LAS surface treatment was preformed. Then, 5 mm diameter Titanium (Ti) discs treated with LAS and GAE method were implanted in a pre-validated rabbit tibia cortical bone model and assessed with histology and histomorphometric measurements. In total, eight New Zealand White adult female rabbits were used. RESULTS: The in vitro cell viability testing with osteoblast-like cells confirmed cytocompatibility of the LAS surface treatment. Further, the rabbit experiment demonstrated a bone-to-implant contact of 68% (±17) for the laser-treated discs and 49% (±21) for the GAE discs 8 weeks after the implantation, which was statistically not different. CONCLUSION: Laser surface treatment gives the same results to the grit-blasting/acid-etched method and thus is a valid alternative to conventional roughening for dental implant materials.
Ljupcho Prodanov; Edwin Lamers; Joop Wolke; Richard Huiberts; John A Jansen; X Frank Walboomers
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-25
Journal Detail:
Title:  Clinical oral implants research     Volume:  -     ISSN:  1600-0501     ISO Abbreviation:  Clin Oral Implants Res     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105713     Medline TA:  Clin Oral Implants Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.
Department of Biomaterials, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
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