Document Detail


In vivo X-ray fluorescence of lead in bone.
MedLine Citation:
PMID:  1464286     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The in vivo measurement of lead in bone by K X-ray fluorescence (K XRF) is becoming an increasingly widely utilized technique for assessing long-term lead dosimetry. Several groups have already reported the development of in vivo measurement systems, the majority adopting the 109Cd/backscatter K XRF technique because of its substantial advantages in terms of a robust measurement, lower detection limit (compared with 57Co/90 degrees), absence of the need for sedation of younger subjects, and lower effective (radiation) dose when calculated according to the most recent guidelines. The advantages of the 109Cd system are primarily a consequence of the physics principles of the technique. The apparatus of each XRF technique is transportable, facilitating easy establishment of mobile laboratory facilities. More research is needed to substantiate claims made for particular XRF technologies, but both L and K XRF techniques provide the possibility of improved understanding of the body's handling of the ubiquitous toxin lead.
Authors:
A C Todd; F E McNeill; B A Fowler
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Environmental research     Volume:  59     ISSN:  0013-9351     ISO Abbreviation:  Environ. Res.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-01-19     Completed Date:  1993-01-19     Revised Date:  2006-10-30    
Medline Journal Info:
Nlm Unique ID:  0147621     Medline TA:  Environ Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  326-35     Citation Subset:  IM    
Affiliation:
University of Maryland, Baltimore 21201.
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MeSH Terms
Descriptor/Qualifier:
Animals
Bone and Bones / chemistry*
Calibration
Edetic Acid / chemistry
Humans
Lead / analysis*,  chemistry
Radiation Dosage
Reproducibility of Results
Spectrometry, X-Ray Emission*
Spectrophotometry, Atomic
Chemical
Reg. No./Substance:
60-00-4/Edetic Acid; 7439-92-1/Lead

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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