| In vivo acid etching effect on bacteria within caries-affected dentin. | |
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MedLine Citation:
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PMID: 20861631 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acid etching procedures may disrupt residual bacteria and contribute to the success of incomplete caries removal followed by adhesive restoration. This study evaluated the in vivo effect of acid etching on cariogenic bacterial activity within affected dentin after minimally invasive treatment of caries lesions. Twenty-eight carious permanent teeth received standardized selective caries removal and random acid etch treatment (E) or not (NE) prior to adhesive restoration. Baseline and 3-month dentin biopsies were collected. The number of bacteria and activity of total bacterial cells and Streptococcus mutans were determined by quantitative PCR and RT-PCR. No statistically significant differences were observed in total bacterial number and activity between E and NE treatments (p > 0.3008). For NE, however, the residual S. mutans bacterial cells were reduced (p = 0.0027), while the activity per cell was significantly increased (p = 0.0010) after reentry at 3 months after restoration. This effect was not observed in group E. Although no significant differences were found between groups, this study suggests that acid etching of affected dentin prior to adhesive restoration may directly or indirectly have an inhibitive effect on the activity of residual cariogenic bacteria. Further research is required to investigate this potential effect. |
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Authors:
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F Gu; E Bresciani; T J Barata; T C Fagundes; M F Navarro; S H Dickens; J C Fenno; M C Peters |
Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2010-09-23 |
Journal Detail:
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Title: Caries research Volume: 44 ISSN: 1421-976X ISO Abbreviation: Caries Res. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-11-16 Completed Date: 2011-03-24 Revised Date: 2011-11-03 |
Medline Journal Info:
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Nlm Unique ID: 0103374 Medline TA: Caries Res Country: Switzerland |
Other Details:
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Languages: eng Pagination: 472-7 Citation Subset: D; IM |
Copyright Information:
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Copyright © 2010 S. Karger AG, Basel. |
Affiliation:
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School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acid Etching, Dental
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methods* Adult Bacteria / drug effects*, isolation & purification Bacterial Load Biopsy Composite Resins / chemistry DNA, Bacterial / analysis Dental Atraumatic Restorative Treatment / methods Dental Bonding Dental Caries / microbiology*, therapy Dental Materials / chemistry, pharmacology* Dentin / microbiology* Female Follow-Up Studies Humans Male Phosphoric Acids / pharmacology* Streptococcus mutans / drug effects, isolation & purification |
| Grant Support | |
ID/Acronym/Agency:
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DE-013298/DE/NIDCR NIH HHS; DE-016499/DE/NIDCR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Composite Resins; 0/DNA, Bacterial; 0/Dental Materials; 0/Epic TMPT; 0/Phosphoric Acids; 7664-38-2/phosphoric acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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