| "In vivo" (35S)methionine interaction with rat liver tRNA. | |
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MedLine Citation:
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PMID: 2775265 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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As part of a study to characterize the methionine role in tumorigenesis, we report that methionine sulfur interacts with rat liver tRNA "in vivo" (35S) radioactivity remained associated to the nucleic acid after a number of treatments, including tRNA deacylation. Similar data were obtained after administration of (methyl-3H) methionine, while no comparable tRNA labelling was detected when the aminoacid labelled in the aliphatic chain was given. Hplc analysis of (35S) tRNA enzymic hydrolysate showed two unidentified UV-absorbing radioactive peaks. NMR spectra of these two peaks did not reveal any thiomethyl group. |
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Authors:
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D Kanduc; M R Rossiello; T Ranieri; E Quagliariello |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biochemical and biophysical research communications Volume: 163 ISSN: 0006-291X ISO Abbreviation: Biochem. Biophys. Res. Commun. Publication Date: 1989 Aug |
Date Detail:
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Created Date: 1989-10-06 Completed Date: 1989-10-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372516 Medline TA: Biochem Biophys Res Commun Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 255-61 Citation Subset: IM |
Affiliation:
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Dipartimento di Biochimica e Biologia Moleculare, Facoltá di Scienze, Universitá di Bari, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals DNA / metabolism Liver / physiology* Magnetic Resonance Spectroscopy Methionine / metabolism* RNA, Transfer / metabolism* Rats Spectrophotometry, Ultraviolet Sulfur* |
| Chemical | |
Reg. No./Substance:
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63-68-3/Methionine; 7704-34-9/Sulfur; 9007-49-2/DNA; 9014-25-9/RNA, Transfer |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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