Document Detail


In vitro susceptibility of Nocardia spp. to a new fluoroquinolone, tosufloxacin (T-3262).
MedLine Citation:
PMID:  2619279     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The in vitro activity of a new fluoroquinolone, tosufloxacin (T-3262), against 111 pathogenic Nocardia strains was studied by an agar dilution method and compared with the activities of other fluoroquinolones. All strains were susceptible to tosufloxacin, and the drug was 2 to 20 times more active than four other quinolones tested. Nocardia farcinica was the Nocardia species most susceptible to tosufloxacin.
Authors:
K Yazawa; Y Mikami; J Uno
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  33     ISSN:  0066-4804     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-03-06     Completed Date:  1990-03-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2140-1     Citation Subset:  IM    
Affiliation:
Department of Experimental Chemotherapy, Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.
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MeSH Terms
Descriptor/Qualifier:
4-Quinolones
Anti-Infective Agents / pharmacology*
Fluoroquinolones*
Humans
Microbial Sensitivity Tests
Naphthyridines*
Nocardia / drug effects*
Nocardia Infections / microbiology
Chemical
Reg. No./Substance:
0/4-Quinolones; 0/Anti-Infective Agents; 0/Fluoroquinolones; 0/Naphthyridines; 100490-36-6/tosufloxacin
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