Document Detail


In vitro selection of a photoresponsive RNA aptamer to hemin.
MedLine Citation:
PMID:  20347300     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A photoresponsive RNA aptamer to hemin was selected in vitro from a random sequence library of RNAs with azobenzene residues. The aptamer bound to hemin under visible light irradiation and was released by ultraviolet light.
Authors:
Mingzhe Liu; Hiroshi Jinmei; Hiroshi Abe; Yoshihiro Ito
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-03-03
Journal Detail:
Title:  Bioorganic & medicinal chemistry letters     Volume:  20     ISSN:  1464-3405     ISO Abbreviation:  Bioorg. Med. Chem. Lett.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-20     Completed Date:  2010-07-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107377     Medline TA:  Bioorg Med Chem Lett     Country:  England    
Other Details:
Languages:  eng     Pagination:  2964-7     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Ltd. All rights reserved.
Affiliation:
Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako-Shi, Saitama 351-0198, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aptamers, Nucleotide / chemistry*
Azo Compounds / chemistry
Base Sequence
Hemin / chemistry*,  metabolism
Light
Molecular Sequence Data
Photochemical Processes
RNA / chemistry*
Ultraviolet Rays
Chemical
Reg. No./Substance:
0/Aptamers, Nucleotide; 0/Azo Compounds; 103-33-3/azobenzene; 16009-13-5/Hemin; 63231-63-0/RNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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