Document Detail


In vitro protein synthesis by oligodendroglial cells.
MedLine Citation:
PMID:  19604847     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Oligodendroglial cells were isolated from spinal cord and brain stem tissue from 30-day-old rats according to the method of Poduslo and Norton except that acetylated trypsin at a concentration of 0.05% was used instead of unmodified trypsin, and the density gradient was slightly changed. Isolated oligodendroglial cells were found to incorporate [U-(14)C]leucine into TCA-insoluble protein up to 120 min. This incorporation was inhibited by cycloheximide and chloramphenicol. Purity of the cell preparation was assessed by phase contrast microscopy and by assay of 2',3'-cyclic nucleotide phosphohydrolase activity.
Authors:
N L Banik; M E Smith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuroscience letters     Volume:  2     ISSN:  0304-3940     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  1976 Jun 
Date Detail:
Created Date:  2009-07-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  235-8     Citation Subset:  -    
Affiliation:
Department of Neurology, Veterans Administration Hospital, Palo Alto U.S.A.
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