Document Detail

In vitro performance comparison of the Sensormedics 3100A and B high-frequency oscillatory ventilators.
MedLine Citation:
PMID:  21037502     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: : The Sensormedics 3100A and 3100B are widely used to provide high-frequency oscillatory ventilation in clinical practice. Infants and children <35 kg are typically oscillated with the 3100A and >35 kg with the 3100B. This study compares the effect of ventilator and patient parameters on delivered tidal volume during high-frequency oscillatory ventilation of a test lung with these devices.
DESIGN: : Laboratory-based study.
SUBJECTS: : Test lung and Sensormedics 3100A and 3100B high-frequency oscillators.
INTERVENTIONS: : A previously validated hot-wire flowmeter (Florian) was placed in series with either a 3100A (n = 3) or 3100B (n = 3) ventilator and a Michigan test lung. Tidal volumes were measured over a range of mean airway pressure, inspiratory:expiratory ratio, frequency, pressure amplitude, and endotracheal tube internal diameter.
MEASUREMENTS AND MAIN RESULTS: : The 3100A and 3100B delivered similar tidal volumes across a range of ventilator parameters for an inspiratory:expiratory ratio of 1:1, differing by <10%. However, at an inspiratory:expiratory ratio of 1:2, there was a statistically significant decrease in tidal volume for the 3100B compared with the 3100A at lower frequencies, which was partially mitigated by increasing pressure amplitude. The difference in the generated pressure and flow waveforms may account for the observed tidal volume differences between the high-frequency oscillatory ventilation models. Delivered tidal volume was highly dependent on endotracheal tube size.
CONCLUSIONS: : Multiple variables contribute to the delivered tidal volume during high-frequency oscillatory ventilation, including ventilator model selection and endotracheal tube size. It is possible that real-time, clinical monitoring of delivered tidal volume during high-frequency oscillatory ventilation would allow better titration and maximize performance of these ventilators in caring for critically ill patients.
Jason W Custer; Andaleeb Ahmed; David W Kaczka; Daniel G Mulreany; David N Hager; Brett A Simon; R Blaine Easley
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies     Volume:  12     ISSN:  1529-7535     ISO Abbreviation:  Pediatr Crit Care Med     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100954653     Medline TA:  Pediatr Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e176-80     Citation Subset:  IM    
From the Departments of Anesthesiology and Critical Care Medicine (JWC, DWK, DGM, BAS, RBE), Pediatrics (JWC, RBE), Biomedical Engineering (DWK), and Medicine (DNH, BAS), Johns Hopkins Medical Institute, Baltimore, MD; Department of Medicine (AA), Good Samaritan Hospital, Baltimore, MD; Departments of Anesthesiology and Pediatrics (RBE), Texas Children's Hospital, Houston, TX.
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