Document Detail


In vitro modulation of caprine monocyte immune functions by ω-3 polyunsaturated fatty acids.
MedLine Citation:
PMID:  20889357     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The in vitro effects of the ω-3 polyunsaturated fatty acids (PUFAs) eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) on phagocytosis and the extracellular respiratory burst in caprine monocytes were assessed. Blood monocytes incubated with increasing concentrations of EPA or DHA (25-200μM) demonstrated increased phagocytosis compared to unexposed monocytes. Generation of reactive oxygen species (ROS) was not markedly affected in the presence of EPA and DHA, except at 200μM, at which concentrations monocyte viability was also reduced.
Authors:
Cristina Lecchi; Guido Invernizzi; Alessandro Agazzi; Mariella Ferroni; Laura Francesca Pisani; Giovanni Savoini; Fabrizio Ceciliani
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Publication Detail:
Type:  Journal Article     Date:  2010-10-02
Journal Detail:
Title:  Veterinary journal (London, England : 1997)     Volume:  189     ISSN:  1532-2971     ISO Abbreviation:  Vet. J.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9706281     Medline TA:  Vet J     Country:  England    
Other Details:
Languages:  eng     Pagination:  353-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Dipartimento di Patologia Animale, Igiene e Sanità Pubblica Veterinaria, Università di Milano, via Celoria 10, 20133 Milano, Italy.
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