Document Detail


In vitro model of invasive pulmonary aspergillosis in the human alveolus.
MedLine Citation:
PMID:  22328387     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Cellular bilayer models can be used to simulate many biological compartments. Here, we describe a cell culture model of the human alveolus that enables the study of early invasive pulmonary aspergillosis. The cellular bilayer is constructed with human alveolar epithelial cells and human pulmonary artery endothelial cells. The cells are grown on a semipermeable polyester membrane. This model can be used to study the pathogenesis, immunobiology and pharmacology of invasive pulmonary aspergillosis.
Authors:
Lea Gregson; William W Hope; Susan J Howard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  845     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  361-7     Citation Subset:  IM    
Affiliation:
The University of Manchester, Manchester, UK.
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