| In vitro maturation of immature oocytes and IVF/ICSI in PCOS patients. | |
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MedLine Citation:
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PMID: 17240801 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In vitro maturation (IVM) programme has developed a culture technique for supporting the growth and maturation of immature oocytes since late of 1980s and has become important in ART methods. The establishment of an IVM programme can yield many advantages. Patients suffering from congenital or postnatal reproductive disorders, such as premature ovarian failure (POF) or polycystic ovarian syndrome (PCOS), can achieve pregnancies by transfer of viable embryos derived from IVM and in vitro fertilisation (IVF) systems. However, the pregnancy rate of IVM-IVF programme for PCO patients was still low. This disadvantage was caused by poor maturation of human immature oocytes and no synchronisation with implantation windows. Recently, application of FSH/hCG priming or optimal maturation medium for proper cytoplasmic maturation improves the success rate of IVM procedures. Indeed, increasing oocyte viability by employing optimised IVM system would also reduce ethical concerns about the disposal of retrieved oocytes with low developmental competence, and concerns about the abuse of the manipulation of human embryos. |
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Authors:
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Kwang Yul Cha; Dong Ryul Lee; Jung Hyun Cho; Tae Ki Yoon |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the Indian Medical Association Volume: 104 ISSN: 0019-5847 ISO Abbreviation: J Indian Med Assoc Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2007-01-23 Completed Date: 2007-02-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7505608 Medline TA: J Indian Med Assoc Country: India |
Other Details:
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Languages: eng Pagination: 446, 448, 473 Citation Subset: IM |
Affiliation:
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Fertility Center of CHA General Hospital, CHA Research Institute, Pochon CHA University College of Medicine, Seoul 135-081, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cells, Cultured Female Fertilization in Vitro* Humans Infertility, Female / etiology, therapy* Oocytes / growth & development* Polycystic Ovary Syndrome / complications, therapy* Pregnancy Pregnancy Rate Sperm Injections, Intracytoplasmic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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