Document Detail


In vitro incorporation of tritiated thymidine by the Sternberg-Reed cells in Hodgkin disease.
MedLine Citation:
PMID:  1161114     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study of the possibilities of new DNA synthesis by the Sternberg-Reed cells of Hodgkin disease was done with tritated thymidine and autoradiography. The results showed that after incubation pulses of 30 and 60 minutes cells with lobulated nucleus, binucleated and trinucleated cells, identifiable to the diagnostic Sternberg-Reed cells, had possibilities of new DNA synthesis. This points to a more dynamic interpretation of this cell that was considered without chances of cnromosome replication.
Authors:
M Marinello; G Tkachenko; J Gavilondo; B Baeza
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neoplasma     Volume:  22     ISSN:  0028-2685     ISO Abbreviation:  Neoplasma     Publication Date:  1975  
Date Detail:
Created Date:  1975-11-20     Completed Date:  1975-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0377266     Medline TA:  Neoplasma     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  185-93     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
DNA, Neoplasm / biosynthesis
Histiocytes / metabolism*,  pathology
Hodgkin Disease / metabolism*,  pathology
Humans
Chemical
Reg. No./Substance:
0/DNA, Neoplasm

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