Document Detail


In vitro immunoglobulin response of fetal B-cells is influenced by perinatal infections and antibiotic treatment: a study in preterm infants.
MedLine Citation:
PMID:  10378393     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
CONCLUSION: The results indicate that perinatal infections and administration of antibiotics depress immunoglobulin secretion in cell cultures. We suggest that in vivo B-cell activity in infected preterm infants, and infants prophylactically receiving antibiotics, could also be depressed and result in decreased immunoglobulin production in these infants.
Authors:
B Cukrowska; R Lodinová-Zádníková; D Sokol; H Tlaskalová-Hogenová
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of pediatrics     Volume:  158     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-07-14     Completed Date:  1999-07-14     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  463-8     Citation Subset:  IM    
Affiliation:
Division of Immunology and Gnotobiology, Prague, Czech Republic. immuno@biomed.cas.cz
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MeSH Terms
Descriptor/Qualifier:
Antibiotic Prophylaxis
B-Lymphocytes / immunology*
Blood Bactericidal Activity
Communicable Diseases / congenital*,  immunology*
Cross Infection / immunology*
Female
Humans
Immunoglobulins / biosynthesis*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / immunology*
Infectious Disease Transmission, Vertical
Pregnancy
Pregnancy Complications, Infectious / immunology*
Sepsis / immunology
Chemical
Reg. No./Substance:
0/Immunoglobulins
Comments/Corrections
Comment In:
Eur J Pediatr. 1999 Jun;158(6):444-5   [PMID:  10378388 ]

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