| In vitro fermentation of lactulose derived oligosaccharides by mixed faecal microbiota. | |
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MedLine Citation:
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PMID: 22292561 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Fermentation properties of oligosaccharides derived from lactulose (OsLu) and lactose (GOS) have been assessed in pH-controlled anaerobic batch cultures using lactulose and Vivinal-GOS as reference carbohydrates. Changes in gut bacterial populations and their metabolic activities were monitored over 24 h by fluorescent in situ hybridization (FISH), and by measurement of short-chain fatty acid (SCFA) production. Lactulose-derived oligosaccharides were selectively fermented by Bifidobacterium and lactic acid bacteria populations producing higher SCFA concentrations compared to GOS. The highest total SCFA production was from Vivinal-GOS lactulose OsLu GOS. Longer incubation periods produced a selective fermentation of oligosaccharides derived from lactulose when they were used as a carbon source reaching the highest selective index scores. The new oligosaccharides may constitute a good alternative to lactulose and they could belong to a new generation of prebiotics to be used as a functional ingredient for improving the composition of gut microflora. |
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Authors:
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Alejandra Cardelle-Cobas; Agustín Olano; Nieves Corzo; Mar Villamiel; Michelle Collins; Sofia Kolida; Robert A Rastall |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-1 |
Journal Detail:
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Title: Journal of agricultural and food chemistry Volume: - ISSN: 1520-5118 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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