| In vitro evaluation of the oxidation efficacy of transgingival photodynamic therapy. | |
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MedLine Citation:
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PMID: 23320555 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Objective. To evaluate the capability of soft laser light to penetrate blood, serum, gingival connective tissue and pure collagen type I. Materials and methods. A 1:1 mixture of methylene blue (MB) and diphenylisobenzofuran (DPBF) was irradiated for 60 s with a diode laser (670 nm, 0.3 W) through blood, serum, gingival connective tissue and collagen type I (2 mm transillumination thickness). The oxidation of DPBF by MB was determined spectrophotometrically by measuring the optical density (oD) at 410 nm. The absorption spectra of DPBF/MB irradiated through MB (1%) and strawberry red solution (3%) served as control. Results. The mean oD of non-irradiated DPBF/MB was 1.98 ± 0.04. Irradiation through MB showed no oxidation of DPBF (1.98 ± 0.02; p > 0.05), while interposition of strawberry red and serum resulted in almost complete oxidation of DPBF (0.13 ± 0.09, 0.06 ± 0.03; p ≤ 0.0001). Irradiation through gingiva and collagen reduced the oxidation of DPBF significantly (1.0 ± 0.04, 0.7 ± 0.04; p ≤ 0.0001), accounting for 50% to 35% of the non-irradiated DPBF/MB solution. Conclusion. Red light from a diode laser can penetrate blood and gingival tissues. However, light absorption for collagen and connective tissue can hamper the oxidation process. |
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Authors:
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Valerie Ronay; Wolfgang Buchalla; Philipp Sahrmann; Thomas Attin; Patrick R Schmidlin |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-16 |
Journal Detail:
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Title: Acta odontologica Scandinavica Volume: - ISSN: 1502-3850 ISO Abbreviation: Acta Odontol. Scand. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370344 Medline TA: Acta Odontol Scand Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Clinic for Preventive Dentistry, Cariology and Periodontology, Center for Dental Medicine, University of Zurich , Switzerland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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