Document Detail

In vitro evaluation of the cytotoxic, hemolytic and clastogenic activities of Rhizostoma pulmo toxin(s).
MedLine Citation:
PMID:  9663699     Owner:  NLM     Status:  MEDLINE    
Cytotoxic, hemolytic and clastogenic activities of Rhizostoma pulmo toxin(s) contained in the jelly tissue free of nematocysts were investigated in mammalian cells with in vitro procedures. At the concentration of 37.6 microg/ml the tissue protein produced the death of 50% V79 cells; a similar potency was observed in terms of hemolytic activity. The toxin(s) was not clastogenic for human lymphocytes in culture at the concentration of 5 microg/ml.
A Allavena; G L Mariottini; A M Carli; S Contini; A Martelli
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Toxicon : official journal of the International Society on Toxinology     Volume:  36     ISSN:  0041-0101     ISO Abbreviation:  Toxicon     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-09-17     Completed Date:  1998-09-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1307333     Medline TA:  Toxicon     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  933-6     Citation Subset:  IM    
Department of Internal Medicine, Pharmacology and Toxicology Unit, University of Genoa, Italy.
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MeSH Terms
Cell Line
Erythrocytes / drug effects*
Lymphocytes / drug effects*
Marine Toxins / toxicity*
Micronucleus Tests
Reg. No./Substance:
0/Marine Toxins

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