| In vitro evaluation of control strategies for an artificial vasculature device. | |
| | |
MedLine Citation:
|
PMID: 17271116 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
|
Ventricular assist devices (VADs) have been used successfully as a bridge to transplant in heart failure patients by unloading ventricular volume and restoring the circulation. An artificial vasculature device (AVD) that may better facilitate myocardial recovery than VAD by controlling the afterload seen by the ejecting heart is being developed. The AVD concept is to enable any user-defined input impedance (IM) with resistance (R) and compliance (C) components. In this study, a pulse duplicator was used to test the efficacy of the AVD concept for two control strategies in an adult mock circulation: (1) R-C in series and (2) 2-element Windkessel (R-C in parallel) using instantaneous impedance position control (IIPC) to maintain a desired value or profile of R and C. In vitro experiments were performed and the resulting cardiovascular pressures, volumes, flows, and the afterload (R and C) seen by the LV during ejection for simulated cardiac failure were recorded and analyzed. Our results indicate that setting the AVD to lower IM reduced LV volume and pressure, restored LV stroke volume, and increased coronary flow. The IIPC control algorithms are better suited to maintain any instantaneous IM or an IM profile, but are susceptible to measurement noise. |
| | |
Authors:
|
J S Glower; R C Cheng; G A Giridharan; K J Gillars; G M Pantalos; K N Litwak; D L Ewert; S C Koenig |
Related Documents
:
|
2252766 - Experience with the sarns centrifugal pump as a ventricular assist device. 9271176 - Long-term mechanical circulatory support as a bridge to transplantation, for recovery f... 12534706 - Recent progress in artificial organ research at tohoku university. 708286 - Intra-aortic balloon pumping: theory and practice. experience with 325 patients. 21742086 - Ischemic heart disease: comprehensive evaluation by cardiovascular magnetic resonance. 10474786 - Beta-adrenergic blocking agents: past, present, and future perspectives. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference Volume: 5 ISSN: 1557-170X ISO Abbreviation: Conf Proc IEEE Eng Med Biol Soc Publication Date: 2004 |
Date Detail:
|
Created Date: 2007-02-02 Completed Date: 2007-06-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101243413 Medline TA: Conf Proc IEEE Eng Med Biol Soc Country: United States |
Other Details:
|
Languages: eng Pagination: 3773-6 Citation Subset: - |
Affiliation:
|
Department of Electrical and Computer Engineering, North Dakota State University, ND, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: An architecture for rapid prototyping of control schemes for artificial ventricles.
Next Document: Dynamic response of the pulmonary circulation in continuous flow artificial heart systems.