| In-vitro evaluation of the PediaSat continuous central venous oxygenation monitoring system. | |
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MedLine Citation:
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PMID: 19952756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVE: In-vitro performance of the PediaSat system for continuous monitoring of central venous oxygen saturation by spectrophotometry has been evaluated. METHODS: PediaSat continuous fibre-optic oximetry catheters were inserted in a black testing chamber, connected with an extracorporeal circuit and filled with human whole blood. Oxygen inflow into the cardiopulmonary bypass system was varied, and the testing chamber was perfused with blood flow of 1000 ml min(-1). Oxygen saturation values measured by PediaSat (S PediaSat O2) were compared with cooximetry (S CO-OX O2) values from simultaneously taken blood samples by Bland-Altman and simple regression analyses. RESULTS: Fifty data pairs were obtained. S PediaSat O2 and S CO-OX O2 values ranged between 28-98 and 24.9-99.5%, respectively. Correlation between S PediSat O2 and S CO-OX O2 was high with an r2 value equal to 0.96 (P < 0.0001). Overall, S PediaSat O2 only slightly overestimated S CO-OX O2 (mean bias +2.9%), and limits of agreement (+/-2 SD of bias) were acceptable (-6.8/+12.6%). Sensitivity and specificity of the first differences of S PediaSat O2 and S CO-OX O2 were 1.0 and 0.92, respectively. Subgroup analysis of S CO-OX O2 values below 70% resulted in an overestimation by S PediaSat O2, with a mean bias of +5.2% and limits of agreement of -4.7 and +15.1%. CONCLUSION: The current version of the PediaSat system does not reliably reflect S CO-OX O2 values below 70%, but it seems to be a useful tool providing an accurate trend of continuous central venous oxygen saturation. |
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Authors:
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Werner Baulig; Nelly Spielmann; Hassan Zaiter; Tomislav Lijovic; Dominique Bettex; Christoph Bürki; Markus Weiss |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: European journal of anaesthesiology Volume: 27 ISSN: 1365-2346 ISO Abbreviation: Eur J Anaesthesiol Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-09 Completed Date: 2010-09-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8411711 Medline TA: Eur J Anaesthesiol Country: England |
Other Details:
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Languages: eng Pagination: 289-94 Citation Subset: IM |
Affiliation:
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Institute of Anaesthesiology, University Hospital Zurich, Zurich, Switzerland. werner.baulig@usz.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Gas Analysis
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instrumentation,
methods,
standards Catheterization, Central Venous / instrumentation*, methods, standards* Fiber Optic Technology / instrumentation, methods, standards Humans Monitoring, Intraoperative / instrumentation*, methods, standards* Oximetry / instrumentation, methods, standards Oxygen Consumption / physiology Spectrophotometry, Infrared / instrumentation, methods, standards |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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