Document Detail


In vitro estimation of iron availability from a range of plant foods: influence of phytate, ascorbate and citrate.
MedLine Citation:
PMID:  3567134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Plant foods were digested in vitro and the proportion of iron which diffused across a semi-permeable membrane was used as an index of Fe availability. The mean (with SEM) Fe diffusibility from a group of eighteen cereals, legumes and nuts was very low, 2.1 (0.25)%, whereas from a group of sixteen fruits and vegetables it was high, 31.7 (1.09)%. The difference between the two food groups was highly significant (P less than 0.001). The results for Fe diffusibility correlated well with literature values for the in vivo absorption of Fe from similar foods (r0.84, P less than 0.01). When phytate, citrate and ascorbate were added to selected foods in amounts corresponding to endogenous levels, only phytate and citrate gave the expected effects on Fe diffusibility. Ascorbate only enhanced Fe diffusibility to the expected extent when it was added in much larger amounts, not normally found in foods. When added to cereal foods, orange juice was found to enhance greatly Fe diffusibility even when its content of ascorbate was completely destroyed by boiling followed by prolonged storage. When citrate and ascorbate were added to cereal foods in amounts equivalent to those found in fresh orange juice, both enhanced Fe diffusibility but citrate was far more effective. It is concluded that phytate is a major inhibitor of Fe diffusibility in cereals, legumes and nuts. However, citrate rather than ascorbate would appear to be the major enhancer of Fe diffusibility from many fruits and vegetables. The implications of the present results are discussed in relation to the relative influence of phytate, citrate and ascorbate on dietary Fe availability.
Authors:
T Hazell; I T Johnson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of nutrition     Volume:  57     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  1987 Mar 
Date Detail:
Created Date:  1987-06-12     Completed Date:  1987-06-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  223-33     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Ascorbic Acid / pharmacology*
Citrates / pharmacology*
Citric Acid
Dose-Response Relationship, Drug
Iron / analysis*
Nutritive Value / drug effects
Phytic Acid / pharmacology*
Plants, Edible / analysis*
Chemical
Reg. No./Substance:
0/Citrates; 50-81-7/Ascorbic Acid; 7439-89-6/Iron; 77-92-9/Citric Acid; 83-86-3/Phytic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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